The frequency of diagnosed primary vaginal cancer in Russia does not exceed 4000 cases. Vaginal cancer can develop in both women with and without hysterectomy. An associative relationship between primary vaginal cancer and infection with high-oncogenic risk human papillomavirus (HPV HPV) types 16 and 33 has been proven. We observed and examined a 62-year-old patient with invasive vaginal cancer after a history of supravaginal amputation of the uterus, as well as carriage of HPV type 16, who, after confirming the diagnosis, was referred to combined chemoradiotherapy.
Insufficient assessment of the significance of the persistence of HPV VCR in women after panhysterectomy, regardless of the presence or absence of a history of CIN, can cause the development of severe vaginal intraepithelial lesions, as well as vaginal cancer.
Journal “Issues of practical colposcopy. Genital infections" No. 1_2023